Year in Review

Foreword from the Directors

Science Articles

Structure of Proteins & DNA

Article: At the Crossroads to Cancer
Development of pathway-specific ERK inhibitors through in silico analysis
Alexander MacKerell and Paul Shapiro
University of Maryland, Baltimore (UMB)

Article: Opening the Glutamate Gate
Binding determinants of glutamate with the glutamate receptor binding domain
Maria Kurnikova and Tatyana Mamonova
Carnegie Mellon University

Earthquake Modeling

Article: Shake, Rattle and Roll
ShakeOut: Numerical simulations of a Mw 7.8 earthquake in Southern California
Jacobo Bielak and David O'Hallaran
Carnegie Mellon University

Corporate Research

Article: A Better Stroke Buster & Smart Shades
Accelerating time-to-market in new-product research and development
John Kalafut (Medrad, Inc.)
Michael Makowski and Jun Deng (PPG Industries)

Evolution and Structure of the Universe

Article: Cooking Stars at MACH 6
The statistics of supersonic isothermal turbulence
Alexei Kritsuk, Paolo Padoan, Mike Norman and Rick Wagner
University of California, San Diego (UCSD)

In Progress